The relationship between inflammation and atherosclerosis is now well established

The relationship between inflammation and atherosclerosis is now well established, and poor oral hygiene is certainly an important potential site in the body for continuous inflammatory stimulation. If the use of a plaque-identifying toothpaste were shown to reduce coronary events, this would represent a simple, easily performed method for reducing the impact of coronary arterial atherosclerosis. I commend the investigators for seriously considering such a trial. The study design would be straightforward, as would be the determination of the cardiovascular outcomes. I for one hope that such a trial will confirm my father’s clinical observations made many decades ago!! The

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